Several medications containing Losartan are being recalled. (Black Press file photo)

Potential ‘human carcinogen’ leads to recall of Losartan-containing drugs

Health Canada is advising that there is no immediate risk to patients taking these medications

Multiple high blood pressure medications containing Losartan are being voluntarily recalled due to a “potentially human carcinogen,” Health Canada says.

Teva Canada, Apotex Inc., Pharmascience Inc,m and Pro Doc Limitée are recalling lots of Losartan-containing drugs because of the potential for a nitrosamine impurity, N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) – a potential human carcinogen meaning that long-term exposure could increase the potential risk of cancer.

As with previous recalls involving nitrosamine impurities, Health Canada is advising that there is no immediate risk to patients taking these medications since the potential risk of cancer is with long-term exposure to the impurities.

“Patients should not stop taking their medication unless advised to do so by their healthcare provider,” Health Canada says.

Teva Canada is voluntarily recalling two lots of combination Losartan/hydrochlorothiazide (HCTZ) tablets after testing of one lot identified levels of NMBA above what is considered reasonably safe if the drug were taken over a lifetime. Apotex Inc., Pharmascience Inc., and Pro Doc Limitée are voluntarily recalling multiple lots of Losartan-containing products as a precaution.

The Losartan active pharmaceutical ingredient (API) in all of the recalled products is manufactured by Hetero Labs Ltd. Unit 1, in India. These recalls represent all lots of drugs distributed in Canada that contain Losartan API manufactured at Hetero Labs Ltd. Unit 1.

Related: Children’s strawberry-flavoured medicines recalled due to faulty safety cap

Related: Brewer’s yeast recall for peanut allergies

Losartan is an angiotensin receptor blocker (ARB) drug, also known as a “sartan.” Sartans are a class of drugs used to treat patients with high blood pressure to help prevent heart attacks and stroke. They are also used in patients who have had heart failure or a recent heart attack. There have been multiple recalls of products containing another sartan, valsartan, in Canada and internationally since July 2018 because of nitrosamine impurities (see links below for more information).

There are alternative products currently available on the Canadian market.

Health Canada continues to monitor the supply situation. Health Canada encourages Canadians to visit drugshortagescanada.ca for information on drug shortages and discontinuances. Patients with questions or concerns about any drug they are taking, including on what to do if that drug is not readily available, should speak to their healthcare professional.

For a list of affected products, visit healthycanadians.gc.ca.


@VernonNews
newstips@vernonmorningstar.com

Like us on Facebook and follow us on Twitter.

Just Posted

Justice Minister discusses rural crime in Lacombe

Minister Doug Schweitzer: “Our democracy is founded on public safety”

Testing winter feed

Testing winter feed lets producers know what nutrients are available

Rural municipalities bracing for possible RCMP cost hike

If proposal from province goes through, it could cost Ponoka County big time

Fed up residents make complaint at Ponoka County council

“Careless” dirt bike, ATV activity spurs residents to call out Ponoka County

VIDEO: Trudeau asks Canada to look to current, not past, actions on race

Liberal leader says he never spoke about the racist photo because he was embarrassed

Judge finds Alberta couple not guilty in toddler son’s death

It was the second trial for the Stephans, who were found guilty by a jury in 2016

Alberta couple charged in toddler son’s death to learn fate from judge

David and Collet Stephan are charged with failing to provide the necessaries of life

Alberta government pitching that small rural areas pay for policing: NDP

Those 291 districts represent about 20 per cent of the Alberta population

Alberta inquiry into oil and gas foes could face legal challenge from Ecojustice

Alberta Premier Jason Kenney has repeatedly accused U.S. charities of bankrolling efforts

Yearbook photo surfaces of Trudeau wearing ‘brownface’ costume in 2001

The report describes the occasion as an ‘Arabian Nights’-themed gala event

‘Troubling, insulting’: NDP Leader Jagmeet Singh reacts to Trudeau’s brownface photo

Jagmeet Singh, leader of the New Democrats, responded with a call for love after Trudeau photos surface

VIDEO: Party leaders react to Trudeau’s brownface photo bombshell

Fallout from Justin Trudeau’s brownface photo, and two other instances, sure to dominate campaign

Most Read